Neuromedina N

Neuromedina N
Identificadores
Símbolo	NN (HGNC: 8038)
Identificadores; externos	EBI: NN; GeneCards: Gen NN; UniProt: NN;
Locus	Cr. 12 q21
Ortólogos
Humano	Ratón
4922
	v; t; e;
	[editar datos en Wikidata]

Neuromedina N
General
Fórmula semidesarrollada	C38H63N7O8
Fórmula estructural
Fórmula molecular	?
Identificadores
Número CAS	102577-25-3
ChemSpider	8115921
PubChem	3025353
	InChI InChI=InChI=1S/C38H63N7O8/c1-7-23(5)31(36(50)42-29(38(52)53)20-22(3)4)43-34(48)28(21-25-14-16-26(46)17-15-25)41-35(49)30-13-11-19-45(30)37(51)32(24(6)8-2)44-33(47)27(40)12-9-10-18-39/h14-17,22-24,27-32,46H,7-13,18-21,39-40H2,1-6H3,(H,41,49)(H,42,50)(H,43,48)(H,44,47)(H,52,53)/t23-,24-,27-,28-,29-,30-,31-,32-/m0/s1; Key: RZMLVIHXZGQADB-YLUGYNJDSA-N
Propiedades físicas
Masa molar	745,473812 g/mol
	[editar datos en Wikidata]

La neuromedina N es un neuropéptido derivado del mismo polipéptido precursor de la neurotensina, con efectos y expresión similares aunque más sutiles que esta.^[2]^[3]^[4]^[5]^[6]^[7]

Referencias

↑ Número CAS
↑ Carraway RE, Mitra SP, Spaulding G (1992). «Posttranslational processing of the neurotensin/neuromedin-N precursor». Annals of the New York Academy of Sciences 668: 1-16. PMID 1463268. doi:10.1111/j.1749-6632.1992.tb27335.x.
↑ Kitabgi P, De Nadai F, Rovère C, Bidard JN (1992). «Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N». Annals of the New York Academy of Sciences 668: 30-42. PMID 1463273. doi:10.1111/j.1749-6632.1992.tb27337.x.
↑ Vincent JP (octubre de 1995). «Neurotensin receptors: binding properties, transduction pathways, and structure». Cellular and Molecular Neurobiology 15 (5): 501-12. PMID 8719037. doi:10.1007/BF02071313.
↑ Adams DH, Hanson GR, Keefe KA (2001). «Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum». Neuroscience 102 (4): 843-51. PMID 11182247. doi:10.1016/S0306-4522(00)00530-3.
↑ Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C (febrero de 2002). «Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity». Biochemical and Biophysical Research Communications 290 (4): 1161-8. PMID 11811984. doi:10.1006/bbrc.2001.6308.
↑ Kitabgi P (octubre de 2006). «Differential processing of pro-neurotensin/neuromedin N and relationship to pro-hormone convertases». Peptides 27 (10): 2508-14. PMID 16904237. doi:10.1016/j.peptides.2006.03.038.

Datos: Q7002397

[1] Número CAS

[pmid1463268-2] Carraway RE, Mitra SP, Spaulding G (1992). «Posttranslational processing of the neurotensin/neuromedin-N precursor». Annals of the New York Academy of Sciences 668: 1-16. PMID 1463268. doi:10.1111/j.1749-6632.1992.tb27335.x.

[pmid1463273-3] Kitabgi P, De Nadai F, Rovère C, Bidard JN (1992). «Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N». Annals of the New York Academy of Sciences 668: 30-42. PMID 1463273. doi:10.1111/j.1749-6632.1992.tb27337.x.

[pmid8719037-4] Vincent JP (octubre de 1995). «Neurotensin receptors: binding properties, transduction pathways, and structure». Cellular and Molecular Neurobiology 15 (5): 501-12. PMID 8719037. doi:10.1007/BF02071313.

[pmid11182247-5] Adams DH, Hanson GR, Keefe KA (2001). «Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum». Neuroscience 102 (4): 843-51. PMID 11182247. doi:10.1016/S0306-4522(00)00530-3.

[pmid11811984-6] Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C (febrero de 2002). «Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity». Biochemical and Biophysical Research Communications 290 (4): 1161-8. PMID 11811984. doi:10.1006/bbrc.2001.6308.

[pmid16904237-7] Kitabgi P (octubre de 2006). «Differential processing of pro-neurotensin/neuromedin N and relationship to pro-hormone convertases». Peptides 27 (10): 2508-14. PMID 16904237. doi:10.1016/j.peptides.2006.03.038.

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