RFWD2

Ring finger and WD repeat domain 2
Identificadores
Símbolos	RFWD2 (HGNC: 17440) COP1; FLJ10416; RNF200
Identificadores; externos	OMIM: 608067 ; EBI: RFWD2; GeneCards: Gen RFWD2; UniProt: RFWD2;
Ortólogos
Humano	Ratón
64326
NP_001001740	n/a
	v; t; e;
	[editar datos en Wikidata]

La ubiquitina proteína ligasa E3 RFWD2 (RFWD2 de sus siglas en inglés "Ring finger and WD repeat domain 2") es una enzima codificada en humanos por el gen RFWD2.^[1]^[2]

Interacciones

La proteína RFWD2 ha demostrado ser capaz de interaccionar con:

c-Jun^[3]^[4]

Referencias

↑ Wang H, Kang D, Deng XW, Wei N (Sep de 1999). «Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1». Curr Biol 9 (13): 711-4. PMID 10395541.
↑ «Entrez Gene: RFWD2 ring finger and WD repeat domain 2».
↑ Wertz, Ingrid E; O'Rourke Karen M, Zhang Zemin, Dornan David, Arnott David, Deshaies Raymond J, Dixit Vishva M (Feb. de 2004). «Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase». Science (United States) 303 (5662): 1371-4. PMID 14739464. doi:10.1126/science.1093549.
↑ Bianchi, Elisabetta; Denti Simona, Catena Raffaella, Rossetti Grazisa, Polo Simona, Gasparian Sona, Putignano Stella, Rogge Lars, Pardi Ruggero (mayo. de 2003). «Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity». J. Biol. Chem. (United States) 278 (22): 19682-90. ISSN 0021-9258. PMID 12615916. doi:10.1074/jbc.M212681200.

Datos: Q18045635

[pmid10395541-1] Wang H, Kang D, Deng XW, Wei N (Sep de 1999). «Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1». Curr Biol 9 (13): 711-4. PMID 10395541.

[entrez-2] «Entrez Gene: RFWD2 ring finger and WD repeat domain 2».

[pmid14739464-3] Wertz, Ingrid E; O'Rourke Karen M, Zhang Zemin, Dornan David, Arnott David, Deshaies Raymond J, Dixit Vishva M (Feb. de 2004). «Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase». Science (United States) 303 (5662): 1371-4. PMID 14739464. doi:10.1126/science.1093549.

[pmid12615916-4] Bianchi, Elisabetta; Denti Simona, Catena Raffaella, Rossetti Grazisa, Polo Simona, Gasparian Sona, Putignano Stella, Rogge Lars, Pardi Ruggero (mayo. de 2003). «Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity». J. Biol. Chem. (United States) 278 (22): 19682-90. ISSN 0021-9258. PMID 12615916. doi:10.1074/jbc.M212681200.

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